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AstraZeneca Submits EUA for LAAB Combo for COVID Prevention

Results from the PROVENT pre-exposure prophylaxis trial showed AZD7442 reduced the risk of developing symptomatic COVID-19 by 77%.

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By: Kristin Brooks

Managing Editor, Contract Pharma

AstraZeneca has submitted a request to the U.S. FDA for an Emergency Use Authorization for AZD7442, its long-acting antibody (LAAB) combination, for prophylaxis of symptomatic COVID-19.   If granted, AZD7442 would be the first LAAB to receive an EUA for COVID-19 prevention. It is the first LAAB with Phase III data demonstrating a statistically significant reduction in the risk of developing symptomatic COVID-19 compared to placebo.   Results from the PROVENT pre-exposure prophylaxis trial sh...

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